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REVIEW ARTICLE
Year : 2019  |  Volume : 9  |  Issue : 1  |  Page : 2-7

The incidence of brain tumours in Iran: A systematic review and meta-analysis


1 Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht; Department of Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran
2 Department of Physiology, Tabriz University of Medical Sciences, Tabriz, Iran
3 Department of Pharmacology, Faculty of Pharmacy, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
4 Department of Public Health, School of Health, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran
5 Department of Biology, Faculty of Science, University of Guilan, Rasht, Iran
6 Department of Neurosurgery, Shiraz University of Medical Sciences, Shiraz, Iran
7 Non-Communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran
8 Department of Epidemiology and Biostatistics, School of Public Health, Shahrekord University of Medical Sciences, Shahrekord, Iran
9 Department of Public Health, Zabol University of Medical Sciences, Zabol; Department of Epidemiology and Biostatistics, Tehran University of Medical Sciences, Tehran, Iran

Correspondence Address:
Hamid Salehiniya
Department of Public Health, Zabol University of Medical Sciences, Zabol; Department of Epidemiology and Biostatistics, Tehran University of Medical Sciences, Tehran
Iran
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/AIHB.AIHB_60_18

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Background: Brain tumours (BTs) constitute approximately 88% of all central nervous system tumours. The present study aimed to determine the age-standardised rate (ASR) of BTs in Iran. Methods: A comprehensive search was conducted on all studies of BTs incidence using Medline/PubMed, Scopus, Embase, Google Scholar and Web of Sciences as international databases and Scientific Information Database, MagIran, IranMedex and IranDoc as Iranian databases until April 2018. This systematic review was done based on the preferred reporting items for systematic reviews and meta-analyses. Results: The primary search yielded 312 relevant studies. A total of 17 studies were included after more detailed retrieval. The results of the random-effect model were demonstrated the ASR of BTs was 4.16 (95% confidence interval [CI], 3.20–5.12) for males and 3.40 (95% CI, 2.67–4.13) for females. Conclusion: The incidence of BTs is lower in Iran compared to other parts of the world. The incidence of nervous system cancers is increasing base on region, geographical, and economic conditions in Iran. Hence, training programmes can be considered to reduce the risk factors, complications of nervous system cancers and early diagnosis of nervous tumors.


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